In Vitro Study of Bone Marrow. Iii. Erythropoiesis in Vitro of Sternal Marrow from Cases of Pernicious Anemia and Lymphatic Leukosis under Therapy
نویسنده
چکیده
CLAUS MUNK PLUM, PH.D. P REVIOUS investigations by one of us (C.M.P.) have demonstrated the possibility of keeping a suspension of bone marrow alive in vitro for several hours for studies on erythropoiesis.3 In the present investigation we have utilized this technic to examine the erythropoietic activity of marrow from normal persons and from cases of pernicious anemia and lymphatic leukosis before and after specific treatment.
منابع مشابه
In vitro study of bone marrow; erythropoiesis in vitro of sternal marrow from cases of pernicious anemia and lymphatic leukosis under therapy.
CLAUS MUNK PLUM, PH.D. P REVIOUS investigations by one of us (C.M.P.) have demonstrated the possibility of keeping a suspension of bone marrow alive in vitro for several hours for studies on erythropoiesis.3 In the present investigation we have utilized this technic to examine the erythropoietic activity of marrow from normal persons and from cases of pernicious anemia and lymphatic leukosis be...
متن کاملCharacteristics of vitamin B12 correction of the abnormal erythropoiesis of pernicious anemia.
T HE DRAMATIC RESPONSE of the pernicious anemia bone marrow to B12 administration has intrigued many investigators and provides an ideal experimental situation for study of conversion of a defective erythropoiesis to normal. By morphological studies with serial bone marrows and in vitro marrow culture technics, investigators have described megaloblast reversion to normoblastic morphology.1-1’ O...
متن کاملBone Marrow Necrosis: Frequency and clinicopathilogical Findings in Marrow Biopsyes
Background and Objectives: Bone marrow necrosis (BMN) is a rare and ominous complication of wide variety of diseases including hematologic malignancy. This study was performed to identify frequency and the underlying associated diseases of marrow necrosis. Materials and Methods: In this descriptive study, totally 850 bone marrow trephine biopsies related to living patients at the Pathology ...
متن کاملHarvesting of bone marrow mesenchymal stem cells from live rats and the in vitro differentiation of bone marrow mesenchymal stem cells into neuron-like cells
In the bone marrow, there are certain populations of stem cell sources with the capacity to differentiate into several different types of cells. Ideally, cell transplants would be readily obtainable, easy to expand and bank, and capable of surviving for sufficient periods of time. Bone marrow mesenchymal stem cells (BM-MSCs) possess all of these characteristics. One of the most important benefi...
متن کاملFalse Negativity of Tc-99m Labeled Sodium Phytate Bone Marrow Imaging Under the Effect of G-CSF Prescription in Aplastic Anemia: A Case Report
Granulocyte colony-stimulating factor (G-CSF) is a hematopoietic cytokine which controls the differentiation and growth of hematopoietic cells in the bone marrow. We report a severe aplastic anemia (SAA) patient with false-negative 99mTc sodium phytate bone marrow imaging findings under concurrent G-CSF therapy. The first bone marrow imaging showed a normal bone marrow activity. However, the bo...
متن کامل